eQTL analysis using gene expression and SNP data
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zen • 0
@zen-22107
Last seen 2.0 years ago

Hello,

I am using RNA-seq data and SNP data to identify expression QTL. I have generated normalized gene expression data. I want to calculate heritability, cis trans variance and eQTL. I found many posts but could not find how to proceed from the beginning with normalized data for samples. My data have genes in columns and samples in rows and the normalized values for each gene and sample. I will appreciate any help. Thank you!

eQTL • 653 views
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Are you referring to the eQTL Bioconductor package or just eQTL generally? If you are referring generally, then your question would be better asked on a more general website for bioinformatics, or, if you are referring to any particular program, you could contact the developers. For example, Oliver Stegle developed PEER: https://github.com/PMBio/peer/wiki

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Thank you, I am referring to eQTL generally.