I didn't see a response to this, and am not an expert, but wanted to point you in the right direction. You should ask this question on the bioconductor mailing list. The site is very much alive at this end (though I'm very close to it, physically), so you'll need to provide some more information about the problems you're experiencing. At a minimum it would help to include the output of the R command sessionInfo() If you're using Windows you might also look at mailing list threads dealing with server proxies. Searchable archives are at http://dir.gmane.org/gmane.science.biology.informatics.conductor this link http://article.gmane.org/gmane.science.biology.informatics.conductor/2 152/match=internet2 and searching for internet2 might be a good start. Martin Debashis Bhattacharya <bhattach at="" simbiosys-biowares.com=""> writes: > The page is either too busy, or there is something seriously wrong with > access to this page. > > Most of the time, trying to reach www.bioconductor.org results in > failure. Only once in a > blue moon, do I get through. > > In fact, thus far, I have not been able to install bioconductor, since > the first source(...) > command from the R command window -- following instruction on > www.bioconductor.org > page, that I did manage to reach, one time -- has failed, every time. > > Please help. > > > > Debashis Bhattacharya. > > ______________________________________________ > R-help at stat.math.ethz.ch mailing list > https://stat.ethz.ch/mailman/listinfo/r-help > PLEASE do read the posting guide http://www.R-project.org/posting- guide.html > and provide commented, minimal, self-contained, reproducible code.