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Hi, Gregory, Could you try invoking ABPkgBuilder directly? Here is a sample script (taken from your email) for example: library (AnnBuilder) data_gb = read.table("probeset_gb.txt" , sep = "\t", header=FALSE, as.is=TRUE) mybase = file.path("probeset_gb.txt") mybasetype= "gb" mydir = getwd() ABPkgBuilder(baseName= mybase, baseMapType = mybasetype, pkgName = "monPackageAnnoted", pkgPath = mydir, organism = "Homo sapiens", version = "1.0.0", author = list (authors = "Greg_Voisin, Amelie Ouellet", maintainer = "voisingreg at ...") ) You have to modify the maintainer email since it is marked by gmane. If it still doesn't work, please write back with the output of "sessionInfo()". thanks nianhua