Re: [Fwd: Bioc Book Chapter] (Gordon K Smyth) Bioconductor Digest, Vol 11, Issue 40
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@christopher-wilkinson-309
Last seen 9.7 years ago
> Message: 6 > Date: Thu, 29 Jan 2004 09:17:31 -0000 > From: "michael watson (IAH-C)" <michael.watson@bbsrc.ac.uk> > Subject: RE: [BioC] Re: [Fwd: Bioc Book Chapter] (Gordon K Smyth) > Biocondu ctor Digest, Vol 11, Issue 38 > To: bioconductor@stat.math.ethz.ch > > Just a quick aside: > > > so I've been looking at 2D spatial norm > > Has anyone published using this method of normalisation? > Its not mentioned in the Yang, Dudoit et.al 2002 NAR paper on normalisation of cDNA data, but it is mentioned briefly in Smyth, G. K., and Speed, T. P. (2003). Normalization of cDNA microarray data. In: METHODS: Selecting Candidate Genes from DNA Array Screens: Application to Neuroscience, D. Carter (ed.). Methods Volume 31, Issue 4, December 2003, pages 265-273. http://www.statsci.org/smyth/pubs/normalize.pdf The reference above is as the bottom of the normalisation entry in limma. I haven't done an extensive literature search beyond this though. Cheers Chris Dr Chris Wilkinson Research Officer (Bioinformatics) | Visiting Research Fellow Child Health Research Institute (CHRI) | Microarray Analysis Group 7th floor, Clarence Rieger Building | Room 121 Women's and Children's Hospital | School of Applied Mathematics 72 King William Rd, North Adelaide, 5006 | The University of Adelaide, 5005 Math's Office (Room 121) Ph: 8303 3714 CHRI Office (CR2 52A) Ph: 8161 6363 Christopher.Wilkinson@adelaide.edu.au http://mag.maths.adelaide.edu.au/crwilkinson.html > ------------------------------ > > ------------------------------
Microarray Normalization Microarray Normalization • 738 views
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@wolfgang-huber-3550
Last seen 20 days ago
EMBL European Molecular Biology Laborat…
Chris Wilkinson wrote: >> >>>so I've been looking at 2D spatial norm >> >>Has anyone published using this method of normalisation? >> Since the spots from different print-tips usually correspond to different spatial sectors on the array, print-tip normalization may also implicitely account for spatial effects. Best wishes Wolfgang ------------------------------------- Wolfgang Huber Division of Molecular Genome Analysis German Cancer Research Center Heidelberg, Germany Phone: +49 6221 424709 Fax: +49 6221 42524709 Http: www.dkfz.de/abt0840/whuber
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