Randomisation / resampling and multiple corrections
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@january-weiner-3999
Last seen 10.3 years ago
Dear all, randomisation or resampling is viewed by some as an alternative to correction for multiple testing such as Bonferroni or Holm. Is there any package implementing such an approach in microarray analysis? Cheers, j. -- -------- Dr. January Weiner 3 -------------------------------------- Max Planck Institute for Infection Biology Charit?platz 1 D-10117 Berlin, Germany Web?? : www.mpiib-berlin.mpg.de Tel? ?? : +49-30-28460514
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@james-w-macdonald-5106
Last seen 2 hours ago
United States
Hi January, The siggenes and samr packages both estimate false discovery via randomization. Best, Jim On 7/22/11 8:10 AM, January Weiner wrote: > Dear all, > > randomisation or resampling is viewed by some as an alternative to > correction for multiple testing such as Bonferroni or Holm. > > Is there any package implementing such an approach in microarray analysis? > > Cheers, > > j. > -- James W. MacDonald, M.S. Biostatistician Douglas Lab University of Michigan Department of Human Genetics 5912 Buhl 1241 E. Catherine St. Ann Arbor MI 48109-5618 734-615-7826 ********************************************************** Electronic Mail is not secure, may not be read every day, and should not be used for urgent or sensitive issues
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Il Jul/22/11 5:31 PM, MacDonald, James ha scritto: > Hi January, > > The siggenes and samr packages both estimate false discovery via > randomization. January, Also have a look at mt.maxT and mt.minP in the multtest package, and perhaps the function 'permax' in the equinymous package. Best wishes Wolfgang > > Best, > > Jim > > > > On 7/22/11 8:10 AM, January Weiner wrote: >> Dear all, >> >> randomisation or resampling is viewed by some as an alternative to >> correction for multiple testing such as Bonferroni or Holm. >> >> Is there any package implementing such an approach in microarray >> analysis? >> >> Cheers, >> >> j. >> > -- Wolfgang Huber EMBL http://www.embl.de/research/units/genome_biology/huber
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