Entering edit mode
The CRAN page shows a publish date of 2012-01-17, so maybe its no longer being maintained. Anybody know if this will be updated for R 3.1.2?
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Why are you asking about a CRAN package on the Bioconductor support site? You should be asking on R-help or asking David James directly.
I am assuming you are running the Mavericks build of R. I think the answer is that the mantainer of the CRAN build machine for Mavericks has not yet installed MySQL, so the RMySQL build fails.
http://www.r-project.org/nosvn/R.check/r-release-osx-x86_64-mavericks/RMySQL-00install.html