**0**wrote:

Hi there,

I was just recently asked to review some normalization techniques for miRNA data but I haven't really worked with R much (don't really understand what is going on in the calcNormFactors function) and I am only a second year undergrad student so I am a little lost when it comes to reading journal articles. I was wondering if anyone had any idea how to implement the TMM normalization technique which was written about in a journal article by Mark Robinson and Alicia Oshlack? I need to implement this in MATLAB for a matrix of miRNA count data so if anyone could point me in the right direction that would be great.

Katherine

**39k**• written 4.4 years ago by katherine.beaulieu14 •

**0**