Hi,
PSICQUIC is an interesting package. it groups multiple interactomics databases.
Specially reactomeFIs provider displays the DIRECTION of the interaction in column 4 (see sample below). I am seeking for this kind of information.
If PSICQUIC does not have this kind of information, is there an other resource that has it?
Karim
Thanks
head(reactomeFIs)
Gene1    Gene2    Annotation    Direction    Score
16-5-5    CDC42    predicted    -    0.85
16-5-5    PARD3    predicted    -    0.92
16-5-5    PARD3B    predicted    -    0.92
16-5-5    PRKCI    predicted    -    0.92
16-5-5    PRKCZ    predicted    -    0.92
16-5-5    RHOJ    predicted    -    0.85
16-5-5    RHOQ    predicted    -    0.85
6M1-16    ADRBK2    PPrel: inhibited by, phosphorylated by    |-    1.00
6M1-16    ARRB2    PPrel: inhibited by    |-    1.00
6M1-16    DKFZP686L0365    PPrel: inhibition    -|    1.00
6M1-16    GNAL    PPrel: activation    ->    1.00
http://reactomews.oicr.on.ca:8080/caBigR3WebApp2014/FIsInGene_121514_with_annotations.txt.zip)
> sessionInfo()
R version 3.2.1 (2015-06-18)
Platform: x86_64-apple-darwin13.4.0 (64-bit)
Running under: OS X 10.10.4 (Yosemite)
but also Kubuntu 14.10
