PSICQUIC is an interesting package. it groups multiple interactomics databases.
Specially reactomeFIs provider displays the DIRECTION of the interaction in column 4 (see sample below). I am seeking for this kind of information.
If PSICQUIC does not have this kind of information, is there an other resource that has it?
Gene1 Gene2 Annotation Direction Score
16-5-5 CDC42 predicted - 0.85
16-5-5 PARD3 predicted - 0.92
16-5-5 PARD3B predicted - 0.92
16-5-5 PRKCI predicted - 0.92
16-5-5 PRKCZ predicted - 0.92
16-5-5 RHOJ predicted - 0.85
16-5-5 RHOQ predicted - 0.85
6M1-16 ADRBK2 PPrel: inhibited by, phosphorylated by |- 1.00
6M1-16 ARRB2 PPrel: inhibited by |- 1.00
6M1-16 DKFZP686L0365 PPrel: inhibition -| 1.00
6M1-16 GNAL PPrel: activation -> 1.00
R version 3.2.1 (2015-06-18)
Platform: x86_64-apple-darwin13.4.0 (64-bit)
Running under: OS X 10.10.4 (Yosemite)
but also Kubuntu 14.10