The Bioconductor website at https://bioconductor.org, will be down for a maximum of 30 minutes for scheduled maintenance on Thursday, December 31st, 12:01PM PST (Seattle time).

This means the web site will be inaccessible and it also means you may not be able to download packages (from within R) at this time. 

The actual maintenance window should be much shorter, but we are allocating 30 minutes just to be safe.

Thanks,
Dan/Bioconductor