I am trying to install rsbml package using bioconductor and encountered the error as :

Error : .onLoad failed in loadNamespace() for 'rsbml', details:
  call: dyn.load(file, DLLpath = DLLpath, ...)
  error: unable to load shared object '/home/haroon/R/x86_64-pc-linux-gnu-library/3.2/rsbml/libs/rsbml.so':
  libsbml.so.5: cannot open shared object file: No such file or directory
Error: loading failed

Command used

source("https://bioconductor.org/biocLite.R")
biocLite("rsbml")

I am on a 64bit linux system with working libSBML as I can read models using python. Here is my session info

R version 3.2.3 (2015-12-10)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 14.04.3 LTS

locale:
 [1] LC_CTYPE=en_IN.UTF-8       LC_NUMERIC=C               LC_TIME=en_IN.UTF-8        LC_COLLATE=en_IN.UTF-8    
 [5] LC_MONETARY=en_IN.UTF-8    LC_MESSAGES=en_IN.UTF-8    LC_PAPER=en_IN.UTF-8       LC_NAME=C                 
 [9] LC_ADDRESS=C               LC_TELEPHONE=C             LC_MEASUREMENT=en_IN.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] BiocInstaller_1.20.1

loaded via a namespace (and not attached):
[1] tools_3.2.3

As mentioned here difficulty loading rsbml I configured PKG_CONFIG_PATH to directory containing libsbml.pc but still no success.

I can launch

>library("libSBML")

as well.

libSBML source was downloaded from http://sourceforge.net/projects/sbml/files/libsbml/5.12.0/stable/

R interface was downloaded from http://sourceforge.net/projects/sbml/files/libsbml/5.12.0/stable/R%20interface/

Any help would be great

Sorry, Martin pointed out that you are on Linux. You probably need to set your LD_LIBRARY_PATH to point to your libsbml lib directory.