How to compute Microarray gene interaction
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shaheryar • 0
@shaheryar-8153
Last seen 7.9 years ago
Korea, Republic Of

I have microarray data and i want to measure gene regulatory network for that i have to compute gene gene interaction. So can one guide me how to compute that and how to put weights on gene graph. What should be the threshold value to be activator or inhibator?

 

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microarray gene interaction GRN r • 1.1k views
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chris86 ▴ 420
@chris86-8408
Last seen 4.9 years ago
UCL, United Kingdom

You can use ARACNE or WGCNA to compute a adjacency matrix, which is the numerical basis for a graph. This can be loaded into cytoscape for visualisation etc.

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