Disease ontology in mouse and possible orthologue in human
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azhar • 0
@azhar-11661
Last seen 7.5 years ago

 

                  Is there any package for lnrna disease ontology or mrna interaction ?  is there any other packges or databsess for gene ontology in mouse hope you will be fine, I am trying to use DOSE package but for disease ontology enrichment analysis I want

1. what kind of input file it can take eg(csv) is okay?

2. which organism it supports I am trying to use for mouse ?

3. I tried for my sample gene lists using Enterz id but every time no map found

4. I used these commands mentioned in pdf


enrichDO(gene, ont = "DO", pvalueCutoff = 0.05, pAdjustMethod = "BH", universe, minGSSize = 10, maxGSSize = 500, qvalueCutoff = 0.2, readable = FALSE)

or

 



data(geneList) gene = names(geneList)[geneList > 1] yy = enrichDO(gene, pvalueCutoff=0.05) summary(yyExamplesenrichResult-

class

 

but every time no map found?

 

thanks

regards

PhD student

CAS TWAS M.Azhar

bioconductor • 1.5k views
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Entering edit mode
Guangchuang Yu ★ 1.2k
@guangchuang-yu-5419
Last seen 2 days ago
China/Guangzhou/Southern Medical Univer…

DOSE is only work for human.

you may use http://www.informatics.jax.org/homology.shtml to map mouse gene to human gene and use DOSE to identify associated disease.

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