Dear Support

I'm working for JnJ using VPCx services. Only recently I'm getting HTTP status '429 Unknown Error' trying to install Bioconductor packages.

>  source("https://bioconductor.org/biocLite.R")
Error in file(filename, "r", encoding = encoding) :
  cannot open the connection to 'https://bioconductor.org/biocLite.R'
In addition: Warning message:
In file(filename, "r", encoding = encoding) :
  cannot open URL 'https://bioconductor.org/biocLite.R': HTTP status was '429 Unknown Error'

I also can't reach this url using Chrome from my AWS Workspace. Other VPCx EC2 instances are also not able to reach that URL. I do can reach this URL from my personal laptop.

I'm trying to figure out if there is something wrong with the AWS/VPCx configuration or might it be possible that Bioconductor is blokking traffic from certain IP sources?

Thx in advance for answering this 'strange' question.

Kind Regards Yves Wetzels

Hi,

You should no longer use that source() command. If you want to install a new package, please use BiocManager. For example, for limma:

BiocManager::install('limma')

Note that you may first have to install BiocManager:

install.packages('BiocManager')

Kevin