PureCN performance of somatic/germline status prediction without matched normal?
1
0
Entering edit mode
twtoal ▴ 10
@twtoal-15473
Last seen 5 months ago
United States

PureCN is able to predict germline vs. somatic status of mutations in the absence of a matched normal. Has a performance evaluation of this capability been published or is otherwise available?

SomaticMutation GermlineMutation PureCN • 904 views
ADD COMMENT
0
Entering edit mode
@markusriester-9875
Last seen 2.5 years ago
United States

On TCGA data: https://ascopubs.org/doi/10.1200/CCI.19.00130

A similar method published shortly after ours with more comprehensive benchmark: https://bmcmedgenomics.biomedcentral.com/articles/10.1186/s12920-017-0296-8

ADD COMMENT

Login before adding your answer.

Traffic: 517 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6