Dear all,

Is there another way to convert "bigwig" files into "count" files that we can use for the analysis of differential binding ? (I do not have access to the packages DiffBind or derfinder) ;

much thanks,

Bogdan

Beside the use of R/BioC libraries, I have found a way that consists in these 2 steps :

a. bedops : wig --> bed

b. bedtools : CoverageBed --counts

Derfinder works well too : https://bioconductor.org/packages/release/bioc/html/derfinder.html