Does DESeq2 work for investigating the gene differential expression before and after the treat but in the same sample?
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Sep • 0
@06de5a1f
Last seen 8 months ago
Germany

Does DESeq2 work for investigating the gene differential expression before and after the treatment but in the same sample? like when we used paired sample t-test that the samples are the same but before and after for example treatment?

I saw that people used condition and time for the design, but in my data time is not specified.

Does DESeq2 work in this situation?

Thanks a lot for your kind help in advance.

DESeq2 • 507 views
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ATpoint ★ 4.1k
@atpoint-13662
Last seen 6 hours ago
Germany

Yes, paired samples are supported. Please see the vignette and one of many posts on 'deseq2 paired' via google.

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Exactly. The vignette has a FAQ at the end and this is one of them.

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