Question: Monocle group sizes
gravatar for ribioinfo
2.5 years ago by
ribioinfo90 wrote:

Hi all,

I would like to perform a differential expression analysis between one group of cells that has 100 cells vs another group that is bigger (2000 cells).

Is it better to choose randomly 100 cells in the 2000 cells in order to have the same numbers of cells in both groups or should I use all the cells?


monocle • 530 views
ADD COMMENTlink written 2.5 years ago by ribioinfo90

Have you found any answer about this issue?
At least I can say that the amount if DE-genes decreases if you sample the bigger group.

ADD REPLYlink written 12 months ago by ksuasteguic0
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