Monocle group sizes
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ribioinfo ▴ 90
@ribioinfo-9434
Last seen 13 months ago

Hi all,

I would like to perform a differential expression analysis between one group of cells that has 100 cells vs another group that is bigger (2000 cells).

Is it better to choose randomly 100 cells in the 2000 cells in order to have the same numbers of cells in both groups or should I use all the cells?

Thanks.

monocle • 661 views
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Have you found any answer about this issue?
At least I can say that the amount if DE-genes decreases if you sample the bigger group.

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