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Question: WGCNA always requires trait data?
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gravatar for adriana.gallego.02
5 months ago by
adriana.gallego.020 wrote:

Hi, I did RNA-seq analysis and Im planning to analyze with WGCNA, I have seen several papers with trait data, but I have a large RNA-seq sampling but few trait data. I was wondering if it is valid do WGCNA just with the expression data and not including any trait data.

Thanks

ADD COMMENTlink modified 5 months ago by Steve Lianoglou12k • written 5 months ago by adriana.gallego.020
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gravatar for Steve Lianoglou
5 months ago by
Genentech
Steve Lianoglou12k wrote:

You don't need (and can't use, AFAIK) trait data for module creation, so if your goal is to just identify modules of co-regulated genes, then your'e good.

Often people want to the associate the activation/expression-level of modules to "traits" but that's a downstream step ...

ADD COMMENTlink written 5 months ago by Steve Lianoglou12k
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