when ever I am try to use AnnotationHub it is return with a below mentioned message.
Pls tell me how can I resolve this problem (using Windows 8)
>>>ah = AnnotationHub()
Error in curl::curl_fetch_memory(url, handle = handle) : 
  Failed to connect to bioconductor.org port 80: Timed out
In addition: Warning message:
database may not be current
  database: ‘C:/Users/Prabir k Das/Documents/AppData/.AnnotationHub/annotationhub.sqlite3’
  reason: Failed to connect to annotationhub.bioconductor.org port 443: Connection refused