I have data from scRNA- seq and Bulk RNA seq data from same cell/tissues. I want to know why there are certain transcripts which show up in single cells are not shown in Bulk RNA seq data. Is it something normal? I would assume that all transcripts in single cell should be represented in bulk data, while the same will not be true for bulk data because you much more transcripts detected in bulk data. But it was weird for me to see single cell RNA seq data had few transcripts which never showed up in bulk RNA seq. Ofcourse i would believe the difference between single cell data with different transcripts number detected but why do we have this variation in single vs bulk data. IS this a technical noise that we should ignore.