Recent ...
Replies
Answer: Are unequal sample sizes in differential gene expression (DGE) analysis a proble
by
Gordon Smyth
51k
No, the imbalance in sample sizes doesn't effect the performance of any of the methods. It is not a problem. You should not be downsampling…
Comment: limma technical repeat correction
by
Gordon Smyth
51k
I have never analysed SomaScan data, so I cannot make any specific recommendations about how to analyse such data. I have however analysed …
Answer: Using voom-transformed counts for unsupervised analyses (PCA, Random Forest, Ela
by
Gordon Smyth
51k
voom() does not transform the data to be homoscedastic. Quite the opposite, it computes precision weights that reflect the mean-variance tr…
Answer: Package needs internet access
by
James W. MacDonald
67k
It's going to need internet access. When you switch to NCBI seqlevels, you are calling this function
```
.fetch_chrom_sizes_from_UCSC_d…
Answer: List of DEGs belonging to an Agilent-single color microarray experiment using Li
by
Gordon Smyth
51k
The first coefficient in your linear model appears to be an intercept term. In this context, you should not be using `method="global"` beca…
Votes
Awards
• All
Popular Question to
Robert Castelo
★
3.4k
Popular Question to
firestar
▴
20
Popular Question to
Ahdee
▴
50
Popular Question to
Dario Strbenac
★
1.5k
Popular Question to
prabin.dm
•
0
Locations
• All
WEHI, Melbourne, Australia, 4 minutes ago
United Kingdom, 5 minutes ago
UPF, Barcelona, Spain, 23 minutes ago
France, 23 minutes ago
EMBL Heidelberg, 27 minutes ago
WEHI, Melbourne, Australia, 4 minutes ago
United Kingdom, 5 minutes ago
UPF, Barcelona, Spain, 23 minutes ago
France, 23 minutes ago
EMBL Heidelberg, 27 minutes ago
Traffic: 820 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6