I am getting this error when trying to biocLite() the latest version:

Error in dyn.load(file, DLLpath = DLLpath, ...) : 
  unable to load shared object '/home/****/R/x86_64-pc-linux-gnu-library/3.4/robustbase/libs/robustbase.so':
  `maximal number of DLLs reached...
ERROR: lazy loading failed for package 'ChAMP'
* removing '/home/****/R/x86_64-pc-linux-gnu-library/3.4/ChAMP'

I know that there is a limit of the number of libraries used at any point, but I have nothing else loaded into the session apart from base packages.

running the following checks: 

> R.utils::gcDLLs()
named list()

> sessionInfo()
R version 3.4.4 (2018-03-15)
Platform: x86_64-pc-linux-gnu (64-bit)
Running under: Ubuntu 16.04.4 LTS

Matrix products: default
BLAS: /usr/lib/libblas/libblas.so.3.6.0
LAPACK: /usr/lib/lapack/liblapack.so.3.6.0

locale:
[1] LC_CTYPE=en_GB.UTF-8       LC_NUMERIC=C               LC_TIME=en_GB.UTF-8        LC_COLLATE=en_GB.UTF-8     LC_MONETARY=en_GB.UTF-8  
[6] LC_MESSAGES=en_GB.UTF-8    LC_PAPER=en_GB.UTF-8       LC_NAME=C                  LC_ADDRESS=C               LC_TELEPHONE=C           
[11] LC_MEASUREMENT=en_GB.UTF-8 LC_IDENTIFICATION=C       

attached base packages:
[1] stats     graphics  grDevices utils     datasets  methods   base     

other attached packages:
[1] BiocInstaller_1.28.0

loaded via a namespace (and not attached):
[1] compiler_3.4.4    tools_3.4.4       R.methodsS3_1.7.1 R.utils_2.6.0     R.oo_1.21.0      

Hello:

The reason is R does not allow users to load more than 100 DLL. But some large packages like ChAMP would load many dependence, and these dependencies would also load many other packages.

I am now fixing this issue, but it's really challenging because I need to decrease some relying packages maybe. A quick solution for you is that you can reset your Renviron file and add one line: R_MAX_NUM_DLLS=512, then this error should be no more.

The Renviron file should be at /usr/local/lib64/R/3.4.4/lib64/R/etc (on my computer), or you can created .Renviron file in your home folder to fix this issue.

Best

Yuan Tian