I have tried to load AnnotationHub to 2 machine (windows 10 and Mac ox ) both attempts failed miserably 

tried different commands+ updated R & R Studio to latest versions ! nothing helped, it seemed it does installed it but i can load it due some other packages getting in the way! masked object ! packages not avoid;avle in compiled versions etc ,  in widows it give me the same error message but the package name  at the end of the error messge called shiny , in mac it is called bit 

also  loadNamespace  consistence on both platform,  I haven't used R in a while so I thought the update will solve the problem ! but it didn't 

this is from my Max machine

> BiocInstaller::biocValid()
[1] TRUE

> library(AnnotationHub)
Loading required package: BiocGenerics
Loading required package: parallel

Attaching package: ‘BiocGenerics’

The following objects are masked from ‘package:parallel’:

    clusterApply, clusterApplyLB, clusterCall, clusterEvalQ, clusterExport, clusterMap,
    parApply, parCapply, parLapply, parLapplyLB, parRapply, parSapply, parSapplyLB

The following objects are masked from ‘package:stats’:

    IQR, mad, sd, var, xtabs

The following objects are masked from ‘package:base’:

    anyDuplicated, append, as.data.frame, basename, cbind, colMeans, colnames, colSums,
    dirname, do.call, duplicated, eval, evalq, Filter, Find, get, grep, grepl, intersect,
    is.unsorted, lapply, lengths, Map, mapply, match, mget, order, paste, pmax, pmax.int,
    pmin, pmin.int, Position, rank, rbind, Reduce, rowMeans, rownames, rowSums, sapply,
    setdiff, sort, table, tapply, union, unique, unsplit, which, which.max, which.min

Error: package or namespace load failed for ‘AnnotationHub’ in loadNamespace(j <- i[[1L]], c(lib.loc, .libPaths()), versionCheck = vI[[j]]):
 there is no package called ‘bit’


> library(AnnotationHub)

Error: package or namespace load failed for ‘AnnotationHub’ in loadNamespace(j <- i[[1L]], c(lib.loc, .libPaths()), versionCheck = vI[[j]]):

 there is no package called ‘bit’

Try installing 'bit' first

biocLite("bit")
biocLite("AnnotationHub")