Dear great R helpers,

As mentioned in the post title, can surrogate variable (sva) batch correction in MeDIP-seq analysis using MEDIPS package? I must admit that I'm very new to such analysis and pretty poor at the concept. I would be deeply gratitude if someone could show me an example for such correction.

Best regards, Kaj

Dear Kaj,

sva normalization is not available in MEDIPS. The diffnorm parameter allows to perform umm or quantile normalization prior to calculating differential enrichment.

All the best,