In a great post previously answered by @Michael Love I have found his response as such
"strainmut.minute15" is the difference between Mut vs WT at minute 15, controlling for baseline. If you add "strainmutvs_wt" to this, you get the LFC for Mutant vs WT at minute 15, not controlling for baseline. So the second one is the observed difference at minute 15 between the two groups (because you added in the change that was present at time=0).
I have seen this answer and similar in different posts.
What I would like to better understand is the highlighted part. What is the exactly difference between
what does it means controlling for baseline?