I have RNA-seq data from several conditions where I have deteremined differentially expressed genes using DESeq2 and I'd now like to perform gene set enrichment analysis on the log2FC values from these comparisons. My question is whether I should use the shrunken log fold changes from "lfcShrink()" function or use the raw log2FC values?
Question: DESeq2 log2FC shrink before GSEA or not?
3 months ago by
bmreilly • 0
bmreilly • 0 wrote:
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