I am performing a scRNA-seq analysis, and will be using the SingleCellExperiment library of Bioconductor to do so. The data for the project comes in both raw and log2(RPKM) formats. Is there a preferable format to use as the input for a SingleCellExperiment object? Does this object work well with RPKM input counts, or is it more advisable to just input raw reads and perform all basic normalization/QC starting from the raw reads? I would really appreciate any advice on this as I am new to Bioconductor and scRNA-seq analysis in general.