I have tried to install MSnbase 2.15.3 after getting this error when loading library(xcms): Error: package ‘MSnbase’ 2.15.0 was found, but >= 2.15.3 is required by ‘xcms’ But the same error is returned. Any suggestions? Here is information:

BiocManager::valid()

* sessionInfo()

R version 4.0.2 (2020-06-22)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19041)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.1252 
[2] LC_CTYPE=English_United States.1252   
[3] LC_MONETARY=English_United States.1252
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.1252    

attached base packages:
[1] parallel  stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
[1] BiocParallel_1.23.2 Biobase_2.49.0      BiocGenerics_0.35.4

loaded via a namespace (and not attached):
[1] BiocManager_1.30.10 compiler_4.0.2      tools_4.0.2        
[4] knitr_1.29          xfun_0.16          

Bioconductor version '3.12'

  * 3 packages out-of-date
  * 0 packages too new
create a valid installation with

  BiocManager::install(c(
    "backports", "DelayedArray", "MSnbase"
  ), update = TRUE, ask = FALSE)

more details: BiocManager::valid()$too_new, BiocManager::valid()$out_of_date

Warning message:
3 packages out-of-date; 0 packages too new 

> traceback()
3: stop(gettextf(msg, sQuote(pkg), current, dep$op, target, sQuote(pkgname)), 
       call. = FALSE, domain = NA)
2: .getRequiredPackages2(pkgInfo, quietly = quietly)
1: library(xcms)



md5-f3753ce86f136eb27731587378a4c380



> sessionInfo()
R version 4.0.2 (2020-06-22)
Platform: x86_64-w64-mingw32/x64 (64-bit)
Running under: Windows 10 x64 (build 19041)

Matrix products: default

locale:
[1] LC_COLLATE=English_United States.1252 
[2] LC_CTYPE=English_United States.1252   
[3] LC_MONETARY=English_United States.1252
[4] LC_NUMERIC=C                          
[5] LC_TIME=English_United States.1252    

attached base packages:
[1] parallel  stats     graphics  grDevices utils     datasets  methods  
[8] base     

other attached packages:
[1] BiocParallel_1.23.2 Biobase_2.49.0      BiocGenerics_0.35.4

loaded via a namespace (and not attached):
[1] BiocManager_1.30.10 compiler_4.0.2      tools_4.0.2        
[4] knitr_1.29          xfun_0.16          

Indeed, there is a timeout on Windows, hence version 2.15.3 not being available - not sure why.

Version 2.15.3 is available as a source package. You will need to first install Rtools and then run BiocManager::install("MSnbase", type = "source") to install the package from source.