converting bedgraph into bigwig
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Bogdan ▴ 660
@bogdan-2367
Last seen 9 hours ago
Palo Alto, CA, USA

HI everyone.

Which packages in R do you recommend to use for operations on the bedgraph files eg conversion from bedgraph into bigwig, union, etc...

Thanks,

Bogdan

bedgraph wiggleplotr bigwig wig • 329 views
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@mgierlinski-7369
Last seen 4 weeks ago
United Kingdom

Bioconductor's rtracklayer can import and export bed, bedgraph and bigwig files. It handles them as GRanges objects - they contain chromosome, range (start, end), strand and any necessary metadata (e.g. score). Bioconductor pacakge GRanges allows for manipulation of these objects, including a union. The combination of the two should do the trick.

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