Sample-specific methylation values using QSEA
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User3088 • 0
@5f840e2d
Last seen 10 months ago
United States

Hello,

Can QSEA package be used for computing sample-specific methylation values? I need tumor and normal samples specific methylation values for given genomic window. The enrichment-based protocol [cfMeDIP-seq] has been followed for sequencing.

As an experimental biologist, I have limited understanding of QSEA package. But I learnt from the tutorial and example dataset, that QSEA identifies DMRs.Therefore, I think QSEA can compute sample-specific methylation values. I need help with the function/command and input data structure that can be used to identify sample-specific methylation values.

Any help is highly appreciated. Thanks in advance.

Ann

DNAMethylation cfMeDIP-seq cfDNA qsea • 393 views
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Hi Ann, Yes, QSEA can be used for this, it will let you calculate beta values for each individual window. What part of the process are you stuck on?

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