WGCNA multiple data sets overlapping analysis
1
0
Entering edit mode
2323982403 ▴ 60
@2323982403-11356
Last seen 3.6 years ago
Ann Arbor

I was analyzing three data sets using wgcna independently.  Each data set gave me several modules and I want to see their overlapping. With the help of the tutorial "Consensus-RelateToFemMods", I could modify some code to generate a overlapping heatmap containing the overlapped counts and p values.  But when it comes assigning highly overlapped modules in different data sets with the same color, I'm a bit confused.

I'm wondering if there is a function for this reassigning module colors according to overlapping status. If there is not, what kind of rules do I have to follow to write my own code?

wgcna multiple data sets overlap • 2.1k views
ADD COMMENT
0
Entering edit mode

You want to compare how much several networks overlap their modules?

You can only compare between two networks to see the overlapping status. So you would need to compare A with B, B with C and A with C, and then extract your conclusions from there. I recommend a venn diagram of the overlapping modules. 

Another option would be to plot them with color bars and see the resulting image how many sections/genes are predominantly of the same color

ADD REPLY
0
Entering edit mode
@peter-langfelder-4469
Last seen 28 days ago
United States

For pairwise matching, use the function matchLabels. You will want to select one of the three sets as a reference set and match the labels of the other two sets to the reference.
 

ADD COMMENT

Login before adding your answer.

Traffic: 744 users visited in the last hour
Help About
FAQ
Access RSS
API
Stats

Use of this site constitutes acceptance of our User Agreement and Privacy Policy.

Powered by the version 2.3.6