Yes, this is because there are no replicates. calculateDiffMeth will run just the fisher’s exact test when there no replicates. That’s why it works when there are no replicates On Tue 17. Jul 2018 at 17:13, nilaycan [bioc] <noreply@bioconductor.org> wrote: > Activity on a post you are following on support.bioconductor.org > > User nilaycan <https: support.bioconductor.org="" u="" 16507=""/> wrote Question: > MethylKit DSS Package <https: support.bioconductor.org="" p="" 111089=""/>: > > Dear Sir/Madam, > > I have tried Methylkit with many datasets and it always worked well using > the function calculateDiffMethDSS. > > However, I am trying to run a data set with no replicates and it crashed > when running calculateDiffMethDSS. It returns the error: > > Error in rowMeans(p) : 'x' must be an array of at least two dimensions > > The same data set works well using calculateDiffMeth instead of > calculateDiffMethDSS. > > Do you have any ideas why? Could it be because that there are no > replicates? > > > Please, let me know if you need more information. > > > > Best Regards, > > Nilay Can > > > ------------------------------ > > Post tags: R, bioconductor, methylation, methylkit > > You may reply via email or visit > MethylKit DSS Package > -- Sent from mobile, excuse the brevity