methyAnalysis M values and Beta Values
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@andrewjskelton73-7074
Last seen 9 months ago
United Kingdom

Hi,

After completing the methyAnalysis Vignette, and following the recommendations; i.e. using the M-Values through the statistical tests.

If I wanted to take the DMR table's "difference" field, and look at the beta value equivalent - is the calculation

2^M / (2^M + 1) = B

????

Thanks

methyAnalysis methyanalysis 450k • 3.9k views
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Pan Du ▴ 80
@pan-du-4535
Last seen 8.9 years ago
United States
Yes. Beta = 2^M/(2^M + 1). But for the difference between M-values, there is no direct way to convert as the difference between Beta-values. You have to convert the M-values as Beta values first and then calculate the difference. On Fri, Mar 6, 2015 at 2:59 AM, andrew.j.skelton73 [bioc] < noreply@bioconductor.org> wrote: > Activity on a post you are following on support.bioconductor.org > > User andrew.j.skelton73 <https: support.bioconductor.org="" u="" 7074=""/> wrote Question: > methyAnalysis M values and Beta Values > <https: support.bioconductor.org="" p="" 65458=""/>: > > Hi, > > After completing the methyAnalysis Vignette, and following the > recommendations; i.e. using the M-Values through the statistical tests. > > If I wanted to take the DMR table's "difference" field, and look at the > beta value equivalent - is the calculation > > 2^M / (2^M + 1) = B > > ???? > > Thanks > > ------------------------------ > > You may reply via email or visit methyAnalysis M values and Beta Values >