**60**wrote:

Hi everyone:

I have peak files in GRanges object which needed to observe overlapping one another, I proceed all possible overlap pairs for given GRanges object, but certainly there is repeated overlap happens. How can I avoid of this sort of repeating that keep overlapping process more neat? Thanks

my objective is once I got paired overlap, do not let repeated overlap happen again. How can I get rid of this repeated overlap for genomic regions in parallel processing? Can anyone propose possible idea to solve this? Thanks

Best regards:

Jurat