I have a differential expression data set, consisting of a list of gene handles, their log2-fold expression change between two conditions, a p-value for that change, and annotated GO terms. It looks basically like this: https://www.dropbox.com/s/bswzujqx07t4lr2/VirtualBox_ubuntubox_11_11_2020_12_44_16.png?dl=0
I am currently working in R, and would like to do a GO term enrichment analysis to get a ranking of GO terms associated with genes that are most up/downregulated. However, I cant find any software/package that is doing that. I have started to get into the "topGO" package, but it seems there is no way to include fold-changes with that one.
Does anybody know how I can achieve my goal or can point me towards something to help me along the way?
Thanks so much!