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Answer: What is the meaning of "CpG interrogation" and "single nucleotide extension(SBE) by James W. MacDonald 64k

There are two types of probes used by Illumina. The type I probes bind directly to the CpG site and have two different probes (one for a me…

Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by Michael Love 41k

Then for the remaining genes that you don't think are DE, just plot like this: ``` dds_sub <- dds[,dds$condition %in% c("x","y")] dropleve…

Comment: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by samer • 0

yes i turned it off @mikelove

Answer: autonomics: example("read_somascan", package = "autonomics") fails, but not on B by Mike Smith ★ 6.2k

It looks like `autonomics` uses `BiocFileCache` to create a local copy of the data and save repeat downloading. Given the (relatively) rec…

Answer: Small RNA-seq Analysis DESEQ2 : Unexpected Significance by Michael Love 41k

I notice you are using `betaPrior=TRUE`. We have set to default and recommended `betaPrior=FALSE` for many years (since version 1.16 in 201…

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Answer: WGCNA documentation not available

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