Question: NMF pre-processsing effect on classification
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gravatar for Seymoo
11 months ago by
Seymoo0
Oslo
Seymoo0 wrote:

I have noticed that when I apply NMF to log2 transformed gene expression data for classification purpose the result are different than if I first do an exponential transformation of the same data matrix. Also, test statistics increase after exponential transformation.

I know that NMF is not applicable to scaled data, which contains negative values, but I am not sure what is the explanation for this observation and appreciate if someone could clarify on this issue.

Regards,

 

ADD COMMENTlink modified 11 months ago • written 11 months ago by Seymoo0
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