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updated 10 weeks ago by
Michael Love
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written 10 weeks ago by
rahaf.nazzal9
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Answer: LRT, pairwise comparisons and p-value adjustment
by
James W. MacDonald
66k
The convention is to adjust only within comparisons. But as the analyst, that's your call.
Comment: Counter-directional LFC shrinkage
by
ennui
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0
Thank you for your response. The `ashr` shrinkage indeed preserves more of the original ranks in the data.
So if I understand correctly, L…
Comment: Counter-directional LFC shrinkage
by
ennui
•
0
I agree it looks offset (and weird). The data is from NGS, not RNAseq, but we still want to see relative abundance between conditions - I t…
Comment: Running ENmix with mouse methylation manifest: readidat error - Error in readman
by
kred
•
0
I tried the latest version and encountered the same issues.
The manifest file I downloaded is the .csv from the following link: https://em…
Comment: Error in gseDO function
by
Javier
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0
As you say it is not a typical experiment of discovery, actually it is carried out in a different way, with a preselected set of genes. We …
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