2.6 years ago
amir
•
0
0
votes
0
replies
1.2k
views
0
votes
3
replies
3.6k
views
0
votes
0
replies
1.1k
views
1
vote
4
replies
2.1k
views
0
votes
0
replies
994
views
updated 6.6 years ago by
Martin Morgan
25k
•
written 6.6 years ago by
jc235601
▴
20
2
votes
0
replies
1.3k
views
6.6 years ago
mstagliamonte
▴
10
0
votes
0
replies
1.3k
views
Recent ...
Replies
Answer: lfc shrinkage estimator in DESeq2
by
plumsgorillas
•
0
You are on the right track. In DESeq2, raw log2 fold changes are often noisy and can be misleading, especially for genes with low counts. A…
Answer: Array weights in dpcDE
by
Gordon Smyth
53k
The uncertainty of quantification is fully accounted for in the dpcDE() analysis, including in the computation of sample weights.
However,…
Answer: lfc shrinkage estimator in DESeq2
by
Michael Love
43k
Try the vignette which has a lot of information on these type of questions.
Comment: limpa analysis advice
by
Gordon Smyth
53k
The DPC slope is beta1. The estimated slopes for your data look pretty low, lower than I've ever used for a real dataset. Nevertheless, as …
Comment: limpa analysis advice
by
SamGG
▴
360
Thanks for your feedback and for reassuring me. :-)
As you suggested, I tried dpcCN() and set the slope to 0.7 in addition to the standard…
Awards
• All
Popular Question to
ja569116
•
0
Popular Question to
julia_mcdonough
•
0
Popular Question to
Ahmed Salah
•
0
Popular Question to
das.traveller
•
0
Popular Question to
ATpoint
★
5.0k
Locations
• All
United States, 14 minutes ago
United States, 1 hour ago
WEHI, Melbourne, Australia, 1 hour ago
The city by the bay, 1 hour ago
United States, 1 hour ago
United States, 14 minutes ago
United States, 1 hour ago
WEHI, Melbourne, Australia, 1 hour ago
The city by the bay, 1 hour ago
United States, 1 hour ago
Traffic: 1541 users visited in the last hour
Use of this site constitutes acceptance of our User Agreement and Privacy Policy.
Powered by the
version 2.3.6
version 2.3.6