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bioinformatics computational biology chemical biology genomics Job

6.4 years ago sergio.martinezcuesta ▴ 10

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Comment: Weird dispersion and volcano plots in DEA with paired samples by Michael Love 39k

I don't think there's any limit to the number of pairs, but for hundreds of coefficients to estimate, I personally would use limma-voom.

Answer: minfi support of illumina Infinium methylationEPIC v2.0 by James W. MacDonald 62k

The annotation packages have not been generated by Bioconductor core, but a [long time contributor has done so][1]. You could install using…

Comment: Time-course, comparison of two groups by boczniak767 ▴ 720

It is likely that I'm wrong, but I think that analysing time trends would be better than analysing each time point separately. It is intuit…

Comment: DEXSeq errors "Error in scan( line ... did not have 3 elements" and "Error in FU by EChambers • 0

Great fix, thank you!

Comment: Time-course, comparison of two groups by Gordon Smyth 47k

Anything is possible but splines will make the analysis more complex and there is no need for it. What makes you think you need splines?

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C: deseq2 normalized data with heatmap

A: deseq2 normalized data with heatmap

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