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Comment: DESeq2 dispersion estimates fitting drastically different based on explanatory v
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Sam
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Here is the explanatory variables![enter image description here][1] uses if that helps address the problem as well
[1]: /media/images/…
Comment: Merge Replicates vs Mixed Model
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abadgerw
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Thanks, @gabrielhoffman
My understanding is that both options would still be mixed models:
Even with technical replicates (3 wells per d…
Comment: Differential Expression Genes as Independent Variables
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Dario Strbenac
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Also, the reason why gene abundance is the dependent variable and is iterated over is that there are far more genes than there are samples …
Comment: rrvgo::calculateSimMatrix() error
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Phila
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Thanks for sharing the solution. It helps me.
[nced cloud][1]
[1]: https://my-ncedcloud-login.us/
Comment: Merge Replicates vs Mixed Model
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gabriel.hoffman
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For your proteomics data, your normalization is correct. I had assumed it was RNA-seq because that is what I think about most. When using…
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