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cmapr
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Can I plot values from LINCS level 4?
cmapR
18 months ago
Alexandre
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Comment: Struggle with the replicates of epic array data
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Comment: scuttle::perFeatureQCMetrics runs very slow for big scRNA-seq data
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Aaron Lun
★ 28k
IIRC loading ~million cells into memory took about 3-5 minutes, but that was with a rather slow filesystem (HDD on a HPC), so YMMV dependin…
Comment: Differential Expression Genes as Independent Variables
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Gordon Smyth
52k
Does not allow mixed models. And is for a different purpose to what your aims seem to be: it's purely for prediction rather than for testin…
Comment: Differential Expression Genes as Independent Variables
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abadgerw
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Thanks! I was thinking about this but do not believe glmnet allows for regularized mixed models unless I am mistaken?
Comment: lfcShrink and alpha value
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cropero
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Thank you for your fast answer, I have everything clear now
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