Bioconductor Comba

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combat sva batch effect comba

updated 9.2 years ago by Vegard Nygaard ▴ 120 • written 9.2 years ago by amoltej ▴ 10

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Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by Gordon Smyth 53k

The design matrix that I described above is completely general. I imagine that it would be possible to use the same approach to generate fu…

Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by chp265 • 0

Cool, glad to hear I wasn't missing some functionality in DESeq2. I don't know that much about the differences between DESeq2 vs edgeR; my …

Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by Michael Love 43k

Yes, so for one thing, note that Gordon has provided code for doing what you are asking in edgeR, which you can go ahead and use. You aske…

Comment: Making a Full Rank Model for Allele-Specific Expression with DESeq2 by chp265 • 0

I don't think DESeq2 has the ability to do multi-contrast comparisons, at least based on what I can understand of the manual; I can pick mu…

Comment: Upcoming Ensembl API and data access changes - new blog post available by Hugo Gruson • 0

Thanks for the update. To be very explicit: what is going to happen to the Biomart service, on which the biomaRt bioconductor package relie…

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Comment: limpa analysis advice

Answer: When to use edgeR or limma

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