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Answer: Generate false reads for testing
by
James W. MacDonald
63k
https://www.bioconductor.org/packages/release/bioc/html/polyester.html
Comment: Adjusting for baseline when having longitudinal data, mixed model and no treat
by
Anna
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20
Yes. But still I prefer using the covariance matrix over fixed effects for power issues. Or at least I wanted to use it as such before our …
Comment: Adjusting for baseline when having longitudinal data, mixed model and no treat
by
Gordon Smyth
47k
No, you are not losing power. The two possible limma analyses (fixed or random Subject effects) are both more powerful than the alternative…
Comment: Adjusting for baseline when having longitudinal data, mixed model and no treat
by
Anna
▴
20
Thanks Gordon
Actually, I am working in the clinical statistics department for the last 5 years, even though a bioinformatician, and the "…
Answer: DESeq2 + analysis question for design with uneven time point design
by
Michael Love
40k
I'd recommend reaching out to a local statistician or someone familiar with linear models in R. Unfortunately, I have to reserve my time on…
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