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Answer: Annotation for EPICv2
by
James W. MacDonald
67k
The CpG you point out is in the intronic region of SHANK2, so will not be in any of the locations you have in your barplot. ![enter ima…
Comment: WGCNA
by
Lluís Revilla Sancho
▴ 750
This is a question of a package outside Bioconductor, it would be best to ask to the maintainer. But i think he moved to industry and the w…
Comment: dmpFinder for other objects
by
James W. MacDonald
67k
Yes, but you should probably use M-values instead of betas (convert using `logit2`). However, `dmpFinder` is just a way to allow people to…
Comment: Highly DE genes but small count difference within conditions
by
Michael Love
42k
This last problem, I don't know how to help with, I think there's high variability here and not many degrees of freedom to overcome that
Answer: [DESeq2] Introduce a bias in DESeq2
by
Michael Love
42k
This is often called an offset in statistical modeling. We have some support site posts about how to do this in DESeq2. Search for posts me…
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Answer: Highly DE genes but small count difference within conditions
Answer: edgeR 4.2.1 compression bug: a minimally reproducible snippet
Trying to use enrichGO
Answer: edgeR 4.2.1 compression bug: a minimally reproducible snippet
Answer: dmpFinder for other objects
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