updated 8.6 years ago by
Gordon Smyth
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written 8.6 years ago by
dk364
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Comment: Volcano plot has many values around zero
by
Michael Love
42k
It's positive over zero or nearly so.
Answer: Volcano plot has many values around zero
by
swbarnes2
★
1.4k
You've got genes with supposedly have a 32-fold difference, and the adjusted p-values are < 1x10-10? That seems odd.
Comment: Volcano plot has many values around zero
by
mjun
•
0
Why this cluster close to 0 with low p value is so distinctive. Is this common? What does it mean and why? Thanks
Comment: Volcano plot has many values around zero
by
swbarnes2
★
1.4k
I don't think this is evidence that the dataset is invalid. It's evidence that your experiment is underpowered, and/or your experimental c…
Comment: Differential Expression Analysis with unbalanced batches without replication bet
by
Gordon Smyth
51k
Have you read the totalVI documentation?, which says:
> **Important**
> We do not recommend using totalVI denoised values in other differ…
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