Bioconductor HLA

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HLA TxDb.Hsapiens.UCSC.hg38.knownGene

updated 4.8 years ago by kayla.interdonato ▴ 160 • written 4.8 years ago by Kamil Slowikowski ▴ 30

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HLA bioconductor bioinformatics

7.4 years ago justinyi10 ▴ 10

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homo.sapiens HLA

updated 7.6 years ago by James W. MacDonald 67k • written 7.6 years ago by a23451352 • 0

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Comment: Volcano plot has many values around zero by Michael Love 42k

It's positive over zero or nearly so.

Answer: Volcano plot has many values around zero by swbarnes2 ★ 1.4k

You've got genes with supposedly have a 32-fold difference, and the adjusted p-values are < 1x10-10? That seems odd.

Comment: Volcano plot has many values around zero by mjun • 0

Why this cluster close to 0 with low p value is so distinctive. Is this common? What does it mean and why? Thanks

Comment: Volcano plot has many values around zero by swbarnes2 ★ 1.4k

I don't think this is evidence that the dataset is invalid. It's evidence that your experiment is underpowered, and/or your experimental c…

Comment: Differential Expression Analysis with unbalanced batches without replication bet by Gordon Smyth 51k

Have you read the totalVI documentation?, which says: > **Important** > We do not recommend using totalVI denoised values in other differ…

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Comment: Weird looking volcano plot

Volcano plot has many values around zero

A: Up/Down Regulated GeneList from edgeR and R

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Popular Question to Dario Strbenac ★ 1.5k

Teacher to Gordon Smyth 51k

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