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You should read the documentation in the package especially the package vignette https://bioconductor.org/packages/release/bioc/html/NuPoP.…
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In a rocker image, this error usually means the Bioconductor install happened as root but the runtime library paths used by the shiny user …
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Are the sequences aligned (i.e., the same width) before running `TileSeqs()`?
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BTW, I tested with no issue on MacOS ARM on our previous github issue.
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The DESeq2 error makes sense, as we've talked about, given that the simple `bplapply` isn't working in your setup.
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