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Comment: Question about using LRT test for time course experiments with DESeq2
by
Denise
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Hi James,
Yes, I understand that the p-values are with respect to the full versus reduced model comparison.
However, the "genes that cha…
Comment: DESeq Input from Salmon + tximport/tximeta
by
Michael Love
42k
Agree.
> for library size and the average transcript length, what additional components will dds <- DESeq(dds) continue to normalize? Will…
Comment: DESeq Input from Salmon + tximport/tximeta
by
ATpoint
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4.5k
> If I use gene_counts_length_scaled.tsv as a metric that has already normalized for library size and the average transcript length
No, o…
Answer: Consistent Decimals In Data After Antibody Array Background Correction Using Lim
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Gordon Smyth
51k
`nec` computes one set of negative control parameters (mu, sigma, alpha) for each sample. For values much larger than the background, the e…
Comment: DESeq Input from Salmon + tximport/tximeta
by
LuciaNhu
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Thank you to the author for the quick reply. If I use `gene_counts_length_scaled.tsv` as a metric that has already normalized for library s…
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